Optimized adaptor trimming

Compared to most conventional tools, proatac offers two key features that optimize the adaptor trimming component of the workflow. First, the trimmers are written in efficient, parallelized C code for optimal performance. Secondly, the adaptor trimming makes no assumptions about the adaptor sequence a priori compared to most tools that require inputting the adaptor sequence ahead of time. These features ensure an improved alignment rate and optimized computational time with little user overhead. The current implementation of these features in proatac uses compiled linux and mac binary files from the PEAT software to perform adaptor trimming.

Bulk and C1-based single cell trimming.

Uses the naive trimming as described above without regard for the particular sequence.

Droplet-based barcode quantification and annotation

More to come but this is important. Need to split samples based on the particular barcode.